Nio (Charming Sister): Atelier Resleriana Character Guide #25

Nio (Charming Sister) offers a unique mix of support, healing and defense. All her skills protect your party from all-out assaults!


Nio, the Charming Sister in Atelier Resleriana, offers a unique blend of offensive and defensive capabilities, making her a valuable asset to your party. Her skillset equips her to effectively respond to various threats, making her a valuable asset in your party.

Nio (CV: Mariya Ise) An apprentice apothecary. She is the younger sister of the alchemist Ayesha. She often spends her time helping her sister or heading out to investigate ruins. Unlike her light-hearted sister, Nio has a much more serious personality. This often leads her to work too hard and worry those around her.

Nio's Resleriana Character Introduction

Basic Information

Character NameNio (Charming Sister)
Initial Rarity When Summoned3 stars
Main RoleDefender

Stats at Level 60


Attribute resistance

fire attributeice attributeLightning attributewind attributeSlash attributeHitting attributespecial attribute

Skill Set

Skill 1: Ladle Swing

AttributeStrikeRangeSingle Target (ONE)
After attacking, reduces own damage received by 5% for 3 attacks and grants Protection to self for 3 turns.
Skill stats and effects depicted are as when character is fully maxed out

Skill 2: Specialty

AttributeStrikeRangeFriendly AoE (ALL)
Reduces all allies' damage received by 20 ~ 24% for 1 attack.
Skill stats and effects depicted are as when character is fully maxed out

Burst Skill: Moonlight Reflection

AttributeStrikeRangeFriendly AoE (ALL)
Restores all allies' HP by 10 ~ 14% at the start of the turn for 5 turns.
Skill stats and effects depicted are as when character is fully maxed out

Character Abilities

Advance All - P.DEF & M. DEF I
Boosts all allies' P. DEF and M.DEF by 5%.
Burn Resistance Up
Boosts Burn resistance by 30%.
These are considered the character's passive skills

Character Gifts

nio gift colorLeftRight

Gift Effects

Fire Shield
Boosts target's Fire resistance by 1 ~ 8% for 1 attack.
Chaser Charge
Boosts damage to stunned enemies by 6 ~ 54%.
Enhanced P./M. Resistance Up [D]
Boosts potency of Received Physical Damage Down and Received Magic Damage Down given to Defenders by 5 ~ 50%.

Gift Bonus

If this character is in the party during Synthesis, the odds of a rank IV or V trait appearing increases by 80%

Character Guide

Combat Guide

Nio's "Ladle Swing" skill showcases her defensive prowess. After attacking, she reduces incoming damage for herself and grants herself a protective barrier, ensuring she can withstand further assaults. This self-preservation allows her to remain on the battlefield longer.

Her "Specialty" ability bolsters the entire party's defense, significantly reducing damage dealt by a single enemy attack. This proactive approach safeguards your entire team, preventing them from falling prey to heavy blows.

Nio's ultimate Burst Skill, "Moonlight Reflection," elevates her to the S-tier. This potent ability automatically restores a portion of all allies' HP at the start of each turn for several turns. This sustained healing proves invaluable in protracted battles, keeping your party healthy and in the fight.

Unlike some defensive characters, Nio lacks the ability to specifically draw enemy attacks. However, her "Ladle Swing" offers a similar benefit by reducing incoming damage. Additionally, her defensive buffs can free up other party members to focus on aggressive tactics.

Recommended Equipment

Note: These recommendations does not consider past or future missable event recipes

Recommended Memoria

Our Master Piece

Nio vs. Sophie: A Different Kind of Defender

Comparisons are often drawn between Nio and Sophie (Profuse Phronesis), another defensive character in Atelier Resleriana. However, it's crucial to recognize their distinct strengths. Sophie excels at attracting enemy attacks, but her defense is limited against attacks that bypass her "taunt" mechanic. In contrast, Nio offers broader protection, safeguarding allies from a wider range of offensive maneuvers.

Ultimately, the choice between Nio and Sophie depends on your specific party composition and the enemies you face. If you require a dedicated tank to soak up damage, Nio is the superior choice. However, if you need a character specifically designed to draw enemy fire and boost the team's offensive output, Sophie might be a better fit.


In conclusion, Nio (Charming Sister) offers a compelling blend of offense and defense, making her a reliable protector for your party in Atelier Resleriana. Whether you need to bolster your team's resilience against single powerful attacks or provide sustained healing throughout a long battle, Nio's skillset has you covered. Thanks for visiting DotGG! For more in-depth Atelier Resleriana guides and character reviews, be sure to bookmark our website so you never miss a beat.

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A. P. Raphael
A. P. Raphael

A. P. Raphael has been playing video games since he was 4 years old and has never stopped loving them. He is also a casual writer who delights in sharing his passion for gaming with others through quirky articles. Sometimes, Raphael also likes to make people laugh with gaming jokes in his writing.

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